Her career encompassed radio, theatrical shorts, feature films, television, record albums (particularly with Stan Freberg), video games, talking toys, and other media. Foray was also one of the early members of ASIFA-Hollywood, the society devoted to promoting and encouraging animation, and is credited with the establishment of the Annie Awards, as well as instrumental to the creation of the Academy Award for Best Animated Feature in 2001. She has a star on the Hollywood Walk of Fame honoring her voice work in television.
Chuck Jones was quoted as saying: "June Foray is not the female Mel Blanc. Mel Blanc was the male June Foray."